The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Oct. 30, 2007
Hatim T. Allawi, Madison, WI (US);
Brad T. Argue, Sun Prairie, WI (US);
Christian Tor Bartholomay, Ames, IA (US);
Luanne Chehak, Janesville, WI (US);
Michelle L. Curtis, Cottage Grove, WI (US);
Peggy S. Eis, Fitchburg, WI (US);
Jeff G. Hall, Waunakee, WI (US);
Hon S. Ip, Madison, WI (US);
Lin Ji, Madison, WI (US);
Michael W. Kaiser, Madison, WI (US);
Robert W. Kwiatkowski, Hopewell Junction, NY (US);
Andrew A. Lukowiak, Stoughton, WI (US);
Victor Lyamichev, Madison, WI (US);
Natalie E. Lyamicheva, Madison, WI (US);
Wupo MA, Madison, WI (US);
Bruce P. Neri, Carlsbad, CA (US);
Sarah M. Olson, Cross Plains, WI (US);
Marilyn C. Olson-munoz, Middleton, WI (US);
James J. Schaefer, Madison, WI (US);
Zbigniev Skrzypczynski, Verona, WI (US);
Tsetska Y. Takova, Madison, WI (US);
Lisa C. Thompson, Madison, WI (US);
Kevin L. Vedvik, Madison, WI (US);
Hatim T. Allawi, Madison, WI (US);
Brad T. Argue, Sun Prairie, WI (US);
Christian Tor Bartholomay, Ames, IA (US);
LuAnne Chehak, Janesville, WI (US);
Michelle L. Curtis, Cottage Grove, WI (US);
Peggy S. Eis, Fitchburg, WI (US);
Jeff G. Hall, Waunakee, WI (US);
Hon S. Ip, Madison, WI (US);
Lin Ji, Madison, WI (US);
Michael W. Kaiser, Madison, WI (US);
Robert W. Kwiatkowski, Hopewell Junction, NY (US);
Andrew A. Lukowiak, Stoughton, WI (US);
Victor Lyamichev, Madison, WI (US);
Natalie E. Lyamicheva, Madison, WI (US);
Wupo Ma, Madison, WI (US);
Bruce P. Neri, Carlsbad, CA (US);
Sarah M. Olson, Cross Plains, WI (US);
Marilyn C. Olson-Munoz, Middleton, WI (US);
James J. Schaefer, Madison, WI (US);
Zbigniev Skrzypczynski, Verona, WI (US);
Tsetska Y. Takova, Madison, WI (US);
Lisa C. Thompson, Madison, WI (US);
Kevin L. Vedvik, Madison, WI (US);
Third Wave Technologies, Inc., Madison, WI (US);
Abstract
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5' nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.