The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Oct. 05, 2005
Applicants:
Martin S. Sinacore, Andover, MA (US);
Mark Leonard, Manchester, NH (US);
Haley A. Laken, Pepperell, MA (US);
Jason Rouse, Londonderry, NH (US);
Inventors:
Martin S. Sinacore, Andover, MA (US);
Mark Leonard, Manchester, NH (US);
Haley A. Laken, Pepperell, MA (US);
Jason Rouse, Londonderry, NH (US);
Assignee:
Wyeth LLC, Madison, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
Abstract
Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.