The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Nov. 17, 2006
Applicants:
Elias Lazarides, La Jolla, CA (US);
Catherine Mary Woods, La Jolla, CA (US);
Mark Bernard, Walnut Creek, CA (US);
Inventors:
Elias Lazarides, La Jolla, CA (US);
Catherine Mary Woods, La Jolla, CA (US);
Mark Bernard, Walnut Creek, CA (US);
Assignee:
Glenmark Pharmaceuticals S.A., La Chaux-De-Fonds, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.