The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Dec. 22, 2004
Ram Pratap, Lucknow-226001, IN;
Mavurapu Satyanarayana, Lucknow-226001, IN;
Chandeshwar Nath, Lucknow-226001, IN;
Ram Raghubir, Lucknow-226001, IN;
Anju Puri, Lucknow-226001, IN;
Ramesh Chander, Lucknow-226001, IN;
Priti Tiwari, Lucknow-226001, IN;
Brajendra Kumar Tripathi, Lucknow-226001, IN;
Arvind Kumar Srivastava, Lucknow-226001, IN;
Ram Pratap, Lucknow-226001, IN;
Mavurapu Satyanarayana, Lucknow-226001, IN;
Chandeshwar Nath, Lucknow-226001, IN;
Ram Raghubir, Lucknow-226001, IN;
Anju Puri, Lucknow-226001, IN;
Ramesh Chander, Lucknow-226001, IN;
Priti Tiwari, Lucknow-226001, IN;
Brajendra Kumar Tripathi, Lucknow-226001, IN;
Arvind Kumar Srivastava, Lucknow-226001, IN;
Other;
Abstract
The present invention provides appropriately substituted chalcones, such as, for example, represented by the structural formula as shown herein below Wherein R1, R2 and R3 are selected from the group consisting of H, OH, O-alkyl, O-phenyl and O-substituted phenyl; B represents Ar—Z—O or RO; where Z is an alkane having up to 5 carbon atoms; R is substituted propanol amino, wherein substituted amino groups are selected from the group consisting of t-butyl, n-butyl, i-butyl, i-propyl, 4-phenyl piperazine-1-yl, 4-(2-methoxyphenyl)-piperazin-1-yl and 3,4-dimethoxy phenethyl; and Ar is thiazolidine-dione methylene phenoxy. The compounds prepared have been demonstrated to exhibit significant antidiabetic effect in various animal models indicating potential for further exploitation.