The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Mar. 21, 2006
Claus Ehrhardt, Lörrach, DE;
Osamu Irie, Tsukuba, JP;
Edwige Liliane Lorthiois, Niffer, FR;
Juergen Klaus Maibaum, Weil-Haltingen, DE;
Nils Ostermann, Binzen, DE;
Holger Sellner, Therwil, CH;
Claus Ehrhardt, Lörrach, DE;
Osamu Irie, Tsukuba, JP;
Edwige Liliane Lorthiois, Niffer, FR;
Juergen Klaus Maibaum, Weil-Haltingen, DE;
Nils Ostermann, Binzen, DE;
Holger Sellner, Therwil, CH;
Novartis AG, Basel, CH;
Abstract
The invention relates to the use of (3,4-di-, 3,3,4-tri, 3,4,4-tri- or 3,3,4,4-tetra-)substituted pyrrolidine compounds for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; compounds that are part of a subclass of these substituted pyrrolidine compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; new compounds that are part of a subclass of these substituted pyrrolidine compounds; pharmaceutical formulations comprising said substituted pyrrolidine compounds, and/or a method of treatment comprising administering said substituted pyrrolidine compounds, a method for the manufacture especially of said new substituted pyrrolidine compounds, as well as novel intermediates, starting materials and/or partial steps for their synthesis.