The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2010

Filed:

Sep. 19, 2008
Applicants:

Richard Clark, Tsukuba, JP;

Atsushi Takemura, Tsukuba, JP;

Nobuhisa Watanabe, Tsukuba, JP;

Osamu Asano, Tsukuba, JP;

Tadashi Nagakura, Tsukuba, JP;

Kimiyo Tabata, Tsukuba, JP;

Inventors:

Richard Clark, Tsukuba, JP;

Atsushi Takemura, Tsukuba, JP;

Nobuhisa Watanabe, Tsukuba, JP;

Osamu Asano, Tsukuba, JP;

Tadashi Nagakura, Tsukuba, JP;

Kimiyo Tabata, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/4439 (2006.01); A61K 31/427 (2006.01); A61K 31/422 (2006.01); A61K 31/4196 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 249/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound represented by the following general formula (1), or a salt thereof has serine protease inhibiting activity, and particularly excellent inhibiting activity against clotting factor VIIa. This compound or a salt thereof is useful as therapeutic and/or prophylactic agents for diseases associated with thrombus formation. [wherein Rrepresents hydrogen, Rrepresents optionally substituted phenyl, etc., Rrepresents optionally substituted C6-10 aryl, etc.].


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