The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Sep. 02, 2008
Hisao Nakai, Mishima-gun, JP;
Yoshifumi Kagamiishi, Mishima-gun, JP;
Hisao Nakai, Mishima-gun, JP;
Yoshifumi Kagamiishi, Mishima-gun, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
Tri-heterocyclic compound of formula (I) wherein each of W, X and Y is carbon or nitrogen; each of U and Z is CR, NR, nitrogen, oxygen, sulfur etc.; A ring is carbocyclic ring, heterocyclic ring; Ris alkyl, alkenyl, alkynyl, NRR, ORetc.; Ris carbocyclic ring, heterocyclic ring;and a pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical comprising them as an active ingredient. A compound of formula (I) is useful, in order to possess corticotropin releasing factor receptor antagonistic activity, for the prevention and/or treatment of depression, anxiety, eating disorder, posttraumatic stress disorder, peptic ulcer, irritable bowl syndrome, Alzheimer's disease, drug addiction or alcohol dependence syndrome etc.