The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Jan. 16, 2008
Suzanne Ostrand-rosenberg, Columbia, MD (US);
Jacobus J. Bosch, Baltimore, MD (US);
Bruce R. Ksander, Belmont, MA (US);
Suzanne Ostrand-Rosenberg, Columbia, MD (US);
Jacobus J. Bosch, Baltimore, MD (US);
Bruce R. Ksander, Belmont, MA (US);
University of Maryland, Baltimore County, Baltimore, MD (US);
Abstract
The present invention relates to tumor cell-based vaccines and methods of using same, wherein the vaccines are based on naturally immune privileged tumor cells that have been genetically modified to express MHC-II restricted peptides derived from endogenously encoded tumor antigens, activate CD4+ T-lymphocytes, provide an array of antigens to which the host is not tolerized and/or induce immunity against the originating tumor cells as well as against metastatic tumor cells.