The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Jul. 19, 2006
Chang Soo Hong, Chicago, IL (US);
Tohru Yamada, Oak Park, IL (US);
Arsenio M. Fialho, Lisbon, PT;
Tapas K. Das Gupta, River Forest, IL (US);
Ananda M. Chakrabarty, Villa Park, IL (US);
Chang Soo Hong, Chicago, IL (US);
Tohru Yamada, Oak Park, IL (US);
Arsenio M. Fialho, Lisbon, PT;
Tapas K. Das Gupta, River Forest, IL (US);
Ananda M. Chakrabarty, Villa Park, IL (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Abstract
The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished by the use of protein transport peptides derived fromouter membrane proteins, such as Laz. The invention also provides synthetic transit peptides comprised of the pentapeptide AAEAP (SEQ ID NO: 25). The invention further discloses methods for treating cancer, and specifically brain cancer, as well as other brain-related conditions. Further, the invention provides methods of imaging and diagnosing cancer, particularly brain cancer.
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