The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Aug. 26, 2004
Applicants:
Toshikazu Nakamura, Okazaki, Sakyo-ku, Kyoto 606-8333, JP;
Kunio Matsumoto, Mino, JP;
Kazuhiro Fukuta, Mino, JP;
Inventors:
Toshikazu Nakamura, Okazaki, Sakyo-ku, Kyoto 606-8333, JP;
Kunio Matsumoto, Mino, JP;
Kazuhiro Fukuta, Mino, JP;
Assignees:
Other;
Kringle Pharma Inc., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/575 (2006.01); A61K 38/22 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a segment of glycosylation-deficient HGF having mutation(s) introduced into an amino acid sequence so as to prevent glycosylation at at least one glycosylation site of a hepatocyte growth factor (HGF), and a method of producing the same. The segment of glycosylation-deficient HGF of the present invention has the same activity as that of a segment of glycosylated HGF, therefore, it is useful as an alternate for a segment of glycosylated HGF.