The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Aug. 17, 2007
Applicants:
Alvin Berger, Raleigh, NC (US);
Imran A. Shah, Chapel Hill, NC (US);
Inventors:
Alvin Berger, Raleigh, NC (US);
Imran A. Shah, Chapel Hill, NC (US);
Assignee:
Metabolon, Inc., Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for the measurement and prediction of response to hepatotoxicants and carcinogens through the detection of metabolites in a mammal are provided. The metabolites can be used as biomarkers, including efficacy biomarkers, surrogate biomarkers, and toxicity biomarkers. The methods find use for early prediction of toxicity, target identification/validation, and monitoring of drug efficacy.