The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2010
Filed:
Dec. 20, 2006
Manabu Sasho, Tokyo, JP;
Keizo Sato, Tsukuba, JP;
Jun Niijima, Tsukuba, JP;
Mamoru Miyazawa, Kamisu, JP;
Shigeto Negi, Tsukuba, JP;
Atsushi Kamada, Tsukuba, JP;
Manabu Sasho, Tokyo, JP;
Keizo Sato, Tsukuba, JP;
Jun Niijima, Tsukuba, JP;
Mamoru Miyazawa, Kamisu, JP;
Shigeto Negi, Tsukuba, JP;
Atsushi Kamada, Tsukuba, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
An object of the present invention is to provide a process, or the like, suitable for the industrialization of effective deprotection reaction without using a toxic solvent as well as to provide a process, or the like, for preparing a water-soluble azole prodrug effectively. The present invention provides a process for preparing a salt represented by Formula (I); (wherein X represents a fluorine atom bonded at position 4 or position 5 of a phenyl group) comprising the steps of: (a) carrying out a deprotection reaction of a compound represented by Formula (II); (wherein X represents a fluorine atom bonded at position 4 or position 5 of a phenyl group)in the presence of a carbocation scavenger.