The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2010

Filed:

Nov. 23, 2009
Applicants:

Andrei Laikhter, Iowa City, IA (US);

Joseph A. Walder, Chicago, IL (US);

Mark Behlke, Coralville, IA (US);

Mikhail Podyminogin, Coralville, IA (US);

Yawfui Yong, Coralville, IA (US);

Inventors:

Andrei Laikhter, Iowa City, IA (US);

Joseph A. Walder, Chicago, IL (US);

Mark Behlke, Coralville, IA (US);

Mikhail Podyminogin, Coralville, IA (US);

Yawfui Yong, Coralville, IA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C07J 21/00 (2006.01); C07D 225/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); C07K 1/00 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.


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