The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2010

Filed:

May. 25, 2005
Applicants:

Hovsep Melkonyan, Princeton, NJ (US);

Angela Cannas, Arbus, IT;

Louis David Tomei, Genazzano, IT;

Samuil R. Umansky, Princeton, NJ (US);

Inventors:

Hovsep Melkonyan, Princeton, NJ (US);

Angela Cannas, Arbus, IT;

Louis David Tomei, Genazzano, IT;

Samuil R. Umansky, Princeton, NJ (US);

Assignee:

TrovaGene, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 9/14 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method for diagnosing and/or monitoring a bacterial or parasitic infection by detection and quantification of the transrenal nucleic acids, derived from bacterial pathogenic agents or from parasites, in urine. The detection method optionally includes the isolation and the purification of the nucleic acids from urine by methods known in the art including pairing with molecular probes that are specific for the pathogenic agents, PCR hybridization, PCR, nested PCR, SSCP, LCR, and SDA. Diagnostic kits based on these detection methods are also claimed.


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