The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2010
Filed:
Sep. 30, 2005
Saverio Minucci, Noverasco Opera, IT;
Pier Giuseppe Pelicci, Opera, IT;
Antonello Mai, Rome, IT;
Marco Ballarini, Milan, IT;
Gaetano Gargiulo, S. Agnello, IT;
Silvio Massa, Rome, IT;
Saverio Minucci, Noverasco Opera, IT;
Pier Giuseppe Pelicci, Opera, IT;
Antonello Mai, Rome, IT;
Marco Ballarini, Milan, IT;
Gaetano Gargiulo, S. Agnello, IT;
Silvio Massa, Rome, IT;
DAC S.R.L., Milan, IT;
Abstract
New inhibitors of histone deacetylases having antitumor activity, and the process of preparation thereof are herein described. These compounds belong to the structural formula (I) where Ris a linear or branched chain containing at least two conjugated double bonds, A is an optionally substituted phenyl or pyridyl ring, Ar is an aryl or heteroaryl group, and Ris hydrogen or alkoxyalkyl. The application also describes the use of said compounds in the treatment of diseases associated to the deregulation of histone deacetylases activity, such as tumors, as well as the relevant pharmaceutical compositions for administration to patients requiring said treatment.