The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2010

Filed:

Sep. 21, 2007
Applicants:

Yue-mei Zhang, Belle Mead, NJ (US);

Bangping Xiang, Bridgewater, NJ (US);

Shyh-ming Yang, High Bridge, NJ (US);

Kenneth Rhodes, Hopkinton, MA (US);

Robert Scannevin, Hopkinton, MA (US);

Paul Jackson, Whitehouse Station, NJ (US);

Davraj Chakravarty, Hillsborough, NJ (US);

Xiaodong Fan, Center Valley, PA (US);

Lawrence J. Wilson, Atlanta, GA (US);

Prabha Karnachi, Hillsborough, NJ (US);

Inventors:

Yue-Mei Zhang, Belle Mead, NJ (US);

Bangping Xiang, Bridgewater, NJ (US);

Shyh-Ming Yang, High Bridge, NJ (US);

Kenneth Rhodes, Hopkinton, MA (US);

Robert Scannevin, Hopkinton, MA (US);

Paul Jackson, Whitehouse Station, NJ (US);

Davraj Chakravarty, Hillsborough, NJ (US);

Xiaodong Fan, Center Valley, PA (US);

Lawrence J. Wilson, Atlanta, GA (US);

Prabha Karnachi, Hillsborough, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 225/02 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula: and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metalloproteases. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.


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