The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2010
Filed:
May. 27, 2004
Applicants:
James E. Hagstrom, Middleton, WI (US);
Julia Hegge, Monona, WI (US);
Hans Herweijer, Brooklyn, WI (US);
Jon A. Wolff, Madison, WI (US);
Inventors:
James E. Hagstrom, Middleton, WI (US);
Julia Hegge, Monona, WI (US);
Hans Herweijer, Brooklyn, WI (US);
Jon A. Wolff, Madison, WI (US);
Assignee:
Roche Madison Inc., Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61M 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
An intravenous delivery method is described that enables delivery of polynucleotides to extravascular cells of a mammalian limb. The method involves the injection of polynucleotides into a distal vein of a limb that is transiently occluded. Polynucleotide delivery is facilitated by rapid injection in sufficient volume to enable extravasation of the solution into surrounding tissue.