The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2010

Filed:

Jun. 11, 2007
Applicants:

Siegfried Ansorge, Hohenwarte, DE;

Uwe Lendeckel, Magdeburg, DE;

Klaus Neubert, Halle, DE;

Dirk Reinhold, Magdeburg, DE;

Robert Vetter, Magdeburg, DE;

Harald Gollnick, Magdeburg, DE;

Inventors:

Siegfried Ansorge, Hohenwarte, DE;

Uwe Lendeckel, Magdeburg, DE;

Klaus Neubert, Halle, DE;

Dirk Reinhold, Magdeburg, DE;

Robert Vetter, Magdeburg, DE;

Harald Gollnick, Magdeburg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/662 (2006.01); A61K 38/05 (2006.01); A61K 38/07 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are combinations of inhibitors of dipeptidyl peptidase IV (DP IV) and of enzymes having the same substrate specificity (DP IV-analogous enzymatic activity) and inhibitors of alanyl aminopeptidase (aminopeptidase N, APN) and of enzymes having the same substrate specificity (APN-analogous enzymatic activity) and use of the same to obtain a more than additive to superadditive inhibition for the treatment of arteriosclerosis, for the treatment of allergic reactions of the type I according to the Gell and Coombs classification and for the treatment of dermatological diseases with follicular and epidermal hyperkeratoses and an enhanced proliferation of keratinocytes.


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