The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2010

Filed:

Jun. 04, 2009
Applicants:

Olga Yurieva, New York, NY (US);

John Kuriyan, Riverdale, NY (US);

Michael E. O'donnell, Hastings-on-Hudson, NY (US);

David Jeruzalmi, New York, NY (US);

Inventors:

Olga Yurieva, New York, NY (US);

John Kuriyan, Riverdale, NY (US);

Michael E. O'Donnell, Hastings-on-Hudson, NY (US);

David Jeruzalmi, New York, NY (US);

Assignee:

The Rockefeller University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

A DNA Polymerase has been identified in a thermophile that functions as a chromosomal replicase. The specific enzyme is a holoenzyme III that has been identified inand corresponds to Polymerase III in. The genes and the polypeptides corresponding to T.th. γ, τ, ε, α and β subunits that they encode are disclosed, as are probes, vectors, methods of preparation and the methods of use. The enzymes of the present invention and their components are particularly well suited for use in procedures for the preparation of DNA, such as PCR, because of the speed and accuracy that they are able to achieve.


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