The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2010
Filed:
Feb. 27, 2009
Applicants:
David J. Bzik, Grantham, NH (US);
Barbara A. Fox, Grantham, NH (US);
Inventors:
David J. Bzik, Grantham, NH (US);
Barbara A. Fox, Grantham, NH (US);
Assignee:
Trustees of Dartmouth College, Hanover, NH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/012 (2006.01); A61K 39/38 (2006.01); C12P 1/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a mutantwhich exhibits enhanced homologous recombination. The mutant of the present invention is a knockout in the KU80-dependent nonhomologous end-joining pathway which finds application in generatinggene knockouts and gene replacements for use in vaccine and drug development.