The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2010
Filed:
Apr. 26, 2004
Michael John Bradley Kutryk, Toronto, CA;
Robert John Cottone, Jr., Fort Lauderdale, FL (US);
Stephen Maxwell Rowland, Miami, FL (US);
Michael John Bradley Kutryk, Toronto, CA;
Robert John Cottone, Jr., Fort Lauderdale, FL (US);
Stephen Maxwell Rowland, Miami, FL (US);
OrbusNeich Medical, Inc., Fort Lauderale, FL (US);
Abstract
A medical device with a coating for capturing target cells in vivo is provided. In particular, the medical device is coated with at least one layer of matrix and a layer of antibodies, antibody fragments or combinations thereof, which bind with specificity to mature or progenitor endothelial cells at various developmental stages to form an endothelial cell layer on the surface of the device. The coated medical device can be, for example, a stent or a synthetic graft and is useful in therapy of diseases such as restenosis, atherosclerosis, and thromboembolic complications.