The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2010

Filed:

Dec. 18, 2006
Applicants:

Antonio Domingo Coto, Barcelona, ES;

Alexander Comely, Barcelona, ES;

Xavier Verdaguer Espaulella, Vic, ES;

Llorenç Rafecas Jané, Llorenç del Penedès, ES;

Inventors:

Antonio Domingo Coto, Barcelona, ES;

Alexander Comely, Barcelona, ES;

Xavier Verdaguer Espaulella, Vic, ES;

Llorenç Rafecas Jané, Llorenç del Penedès, ES;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for the preparation of (S)-omeprazole from racemic omeprazole via the formation of an inclusion complex with (S)-1,1,2-triphenyl-1,2-ethanediol. (S)-Omeprazole is recovered in a substantially optically pure form either in neutral form or as a pharmaceutically acceptable salt or as its solvates including hydrates. The (S)-omeprazole 2[(S)-1,1,2-triphenyl-1,2-ethanediol] inclusion complex is new. This resolution process proceeds with high yields and high optical purity.


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