The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2010

Filed:

Dec. 18, 2006
Applicants:

Denis Deschenes, Dorval, CA;

Rejean Fortin, Montreal, CA;

Chun Sing LI, Dollard-des-Ormeaux, CA;

Renata M. Oballa, Kirkland, CA;

Yeeman K. Ramtohul, Pierrefonds, CA;

Inventors:

Denis Deschenes, Dorval, CA;

Rejean Fortin, Montreal, CA;

Chun Sing Li, Dollard-des-Ormeaux, CA;

Renata M. Oballa, Kirkland, CA;

Yeeman K. Ramtohul, Pierrefonds, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 31/501 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 35/00 (2006.01); A61P 3/10 (2006.01); A61P 3/04 (2006.01); A61P 3/00 (2006.01); A61P 1/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; lipid disorders; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; fatty liver disease and cancer.


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