The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2010

Filed:

Oct. 28, 2008
Applicants:

Jitendra Ramanlal Dave, Gaithersburg, MD (US);

Changping Yao, Gaithersburg, MD (US);

Anthony Joseph Williams, Middletown, MD (US);

Xi-chun May, Laurel, MD (US);

Frank Casper Tortella, Columbia, MD (US);

Ka-wang Kevin Wang, Gainsville, FL (US);

Ronald Lawrence Hayes, Gainsville, FL (US);

Inventors:

Jitendra Ramanlal Dave, Gaithersburg, MD (US);

Changping Yao, Gaithersburg, MD (US);

Anthony Joseph Williams, Middletown, MD (US);

Xi-Chun May, Laurel, MD (US);

Frank Casper Tortella, Columbia, MD (US);

Ka-Wang Kevin Wang, Gainsville, FL (US);

Ronald Lawrence Hayes, Gainsville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/567 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
Abstract

A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum).


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