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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7799349 B1

PDFFull Text
Expired
Date of Patent:
Sep. 21, 2010

Filed:

Feb. 28, 2005

Therapeutic angiogenesis by bone marrow-derived cell transplantation in myocardial ischemic tissue and skeletal muscle ischemic tissue

Applicants:

Takafumi Ueno, Kurume, JP;

Toyoaki Murohara, Fukuoka, JP;

Keith Allen Robinson, Norcross, GA (US);

Nicolas A. F. Chronos, Atlanta, GA (US);

Sam Baldwin, Newton, MA (US);

Maria Palasis, Wellesley, MA (US);

Inventors:

Takafumi Ueno, Kurume, JP;

Toyoaki Murohara, Fukuoka, JP;

Keith Allen Robinson, Norcross, GA (US);

Nicolas A. F. Chronos, Atlanta, GA (US);

Sam Baldwin, Newton, MA (US);

Maria Palasis, Wellesley, MA (US);

Assignee:

Boston Scientific Scimed, Inc., Maple Grove, MN (US);

Attorney:

Kenyon & Kenyon LLP

Primary Examiner:

Michail A Belyavskyi

Int. Cl.
CPC ...
A61K 35/28 (2006.01); A61K 35/26 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides methods of forming new blood vessels in diseased or damaged tissue in a subject, methods of increasing blood flow to diseased or damaged tissue in a subject, and methods of increasing angiogenesis in diseased tissue in a subject, which methods comprise: a) isolating autologous bone marrow-mononuclear cells from the subject; and b) transplanting locally into the diseased or damaged tissue an effective amount of the autologous bone-marrow mononuclear cells, thereby forming new blood vessels in the diseased or damaged tissue. The new blood vessels may be capillaries or collateral vessels in ischemic tissue or any site of angiogenesis. Also provided are methods of treating tissue in disease or injury by local transplantation with an effective amount of the autologous bone marrow-mononuclear cells so as to induce vascularization in such diseased tissue.

Find Patent Forward Citations

Ueno, Takafumi. (2010). Therapeutic angiogenesis by bone marrow-derived cell transplantation in myocardial ischemic tissue and skeletal muscle ischemic tissue (U.S. Patent No. 7799349). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7799349

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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