The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2010

Filed:

Jan. 25, 2007
Applicants:

Chih Yung Ho, Lansdale, PA (US);

Bengt Anders Brunmark, LaJolla, CA (US);

Stuart Emanuel, Doylestown, PA (US);

Robert A. Galemmo, Jr., Collegeville, PA (US);

Dana L. Johnson, Upper Black Eddy, PA (US);

Donald W. Ludovici, Quakertown, PA (US);

Umar Maharoof, North Wales, PA (US);

Jay M. Mei, North Wales, PA (US);

Jan L. Sechler, Doylestown, PA (US);

Eric D. Strobel, Hatboro, PA (US);

Robert W. Tuman, Chalfont, PA (US);

Hwa Kwo Yen, Malvern, PA (US);

Inventors:

Chih Yung Ho, Lansdale, PA (US);

Bengt Anders Brunmark, LaJolla, CA (US);

Stuart Emanuel, Doylestown, PA (US);

Robert A. Galemmo, Jr., Collegeville, PA (US);

Dana L. Johnson, Upper Black Eddy, PA (US);

Donald W. Ludovici, Quakertown, PA (US);

Umar Maharoof, North Wales, PA (US);

Jay M. Mei, North Wales, PA (US);

Jan L. Sechler, Doylestown, PA (US);

Eric D. Strobel, Hatboro, PA (US);

Robert W. Tuman, Chalfont, PA (US);

Hwa Kwo Yen, Malvern, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); A61K 31/4439 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.


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