The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Aug. 22, 2005
Sandro Belvedere, Verona, IT;
Christopher Laurence Hamblett, Boston, MA (US);
Thomas A. Miller, Brookline, MA (US);
David J. Witter, Norfolk, MA (US);
Jiaming Yan, New York, NY (US);
Sandro Belvedere, Verona, IT;
Christopher Laurence Hamblett, Boston, MA (US);
Thomas A. Miller, Brookline, MA (US);
David J. Witter, Norfolk, MA (US);
Jiaming Yan, New York, NY (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The invention relates to hydroxamic acid derivatives having carbamate linkage with the structural formula that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous systems (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.