The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Sep. 21, 2007
Sylvie Baltzer, Strausbourg, FR;
Bruno Schoentjes, Bois-Guillaume, FR;
Viviane Van Dorsselaer, Strasbourg, FR;
Sylvie Baltzer, Strausbourg, FR;
Bruno Schoentjes, Bois-Guillaume, FR;
Viviane Van Dorsselaer, Strasbourg, FR;
Sanofi-Aventis, Paris, FR;
Abstract
This invention discloses and claims a method of treatment of a disease as defined herein using a compound conforming to the general formula (I): Wherein R, R, R', R, Rand Rare as described herein. Specifically, the compounds of the present invention exhibit an inhibitory effect on the production of β-amyloid peptide (β-A4) by inhibition of gamma protease. Therefore, the compounds of the present invention are useful in the treatment of pathologies such as senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy and/or cerebrovascular disorders.