The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Jan. 06, 2005
Ian Gilbert, Dundee, GB;
Corinne Nguyen, Cardiff, GB;
Gian Filippo Ruda, Dundee, GB;
Alessandro Schipani, Dundee, GB;
Ganasan Kasinathan, Cardiff, GB;
Nils-gunnar Johansson, Enhörna, SE;
Dolores Gonzalez Pacanowska, Granada, ES;
Ian Gilbert, Dundee, GB;
Corinne Nguyen, Cardiff, GB;
Gian Filippo Ruda, Dundee, GB;
Alessandro Schipani, Dundee, GB;
Ganasan Kasinathan, Cardiff, GB;
Nils-Gunnar Johansson, Enhörna, SE;
Dolores Gonzalez Pacanowska, Granada, ES;
Medivir AB, Huddinge, SE;
Abstract
Deoxyuridine derivatives of the formula (I) where Ris H or various substituents; D is —NHCO—, —CONH—, -0-, —C(═O)—, —CH═CH, —C≡C—, —NR—; Ris hydrogen or various substituents; Ris H, C-Calkyl, C-Calkanoyl; E is Si or C; R, Rand Rare independently selected from C-Calkyl, C-Calkenyl, C-Calkynyl or a stable monocyclic, bicyclic or tricyclic ring system; G is —O—, —S—, —CHR—, —C(═O)—; J is —CH—, or when G is CHRmay also be —O— or —NH—; Ris H, F, —CH, —CHNH, —CHOH; —OHRis H, F, —CH, —CHNH, —CHOH, —CH(OH)CH, CH(NH)CH; or Rand Rtogether define an olefinic bond, or together form a —CH-group, thereby defining a cis or trans cyclopropyl group; have utility in the prophylaxis or treatment of protozoal diseases such as malaria.