The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Mar. 19, 2003
Thomas J. Gardella, Needham, MA (US);
John T. Potts, Jr., Charlestown, MA (US);
Henry M. Kronenberg, Boston, MA (US);
Naoto Shimizu, Shizuoka, JP;
Thomas J. Gardella, Needham, MA (US);
John T. Potts, Jr., Charlestown, MA (US);
Henry M. Kronenberg, Boston, MA (US);
Naoto Shimizu, Shizuoka, JP;
The General Hospital Corporation, Boston, MA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention relates to conformationally constrained parathyroid hormone (PTH) analogs and derivatives of those analogs. The invention also provides methods of preparing and using the PTH analogs. Further, the invention encompasses compositions and methods for use in limiting undesired bone loss in a vertebrate at risk of such bone loss, in treating conditions that are characterized by undesired bone loss or by the need for bone growth, e.g. in treating fractures or cartilage disorders and for raising camp levels in cells where deemed necessary.