The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Aug. 29, 2003
Timothy J. O'brien, Little Rock, AR (US);
Martin J. Cannon, Little Rock, AR (US);
Alessandro Santin, Little Rock, AR (US);
John Beard, Little Rock, AR (US);
Kazushi Shigemasa, Hiroshima, JP;
Timothy J. O'Brien, Little Rock, AR (US);
Martin J. Cannon, Little Rock, AR (US);
Alessandro Santin, Little Rock, AR (US);
John Beard, Little Rock, AR (US);
Kazushi Shigemasa, Hiroshima, JP;
Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
The present invention discloses the protease hepsin is specifically over-expressed in ovarian and other malignancies. A number of hepsin peptides can induce immune responses to hepsin, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies. There is also provided a hepsin protein variant that is useful as a marker for ovarian cancer cells, prostate cancer cells or kidney cancer cells.