The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2010

Filed:

Mar. 30, 2007
Applicants:

Mahendra S. Rao, Salt Lake City, UT (US);

Mark Noble, Brighton, NY (US);

Margot Mayer-proschel, Pittsford, NY (US);

Inventors:

Mahendra S. Rao, Salt Lake City, UT (US);

Mark Noble, Brighton, NY (US);

Margot Mayer-Proschel, Pittsford, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5E-NCAMglial-restricted precursor (GRP) cells are capable of differentiating into oligodendrocytes, A2B5process-bearing astrocytes, and A2B5fibroblast-like astrocytes, but not into neurons. GRP cells can be maintained by regeneration in culture. GRP cells differ from oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells in growth factor requirements, morphology, and progeny. Methods of use of GRP cells are also disclosed.


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