The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Dec. 07, 2007
Mirko Lehmann, Ebnat-Kappel, CH;
Martin Brischwein, München, DE;
Werner Baumann, Buhl, DE;
Ralf Ehret, Merdingen, DE;
Ingo Freund, Freiburg, DE;
Mirko Lehmann, Ebnat-Kappel, CH;
Martin Brischwein, München, DE;
Werner Baumann, Buhl, DE;
Ralf Ehret, Merdingen, DE;
Ingo Freund, Freiburg, DE;
Micronas GmbH, Freiburg, DE;
Abstract
A device for investigating activities of cell cultures in a liquid culture medium includes a receptacle for the culture medium, and one or more sensors for measurement of cell culture activities. An opening for adding and removing liquid culture medium is provided. A separating element can be placed close to the receptacle bottom, forming a partial space with a small volume relative to the entire volume. A flow channel that communicates with the small volume and the reservoir and/or the sensors are placed in the small volume partial space. By adjustment of the separating element distance from the receptacle bottom, a microreaction volume exactly fitting the current requirements is obtained. For regeneration of the cell culture solution in the small volume partial space, the separating element can be elevated and depressed, or liquid can be injected into the small volume by the through-flow channel, providing convective mixing of fresh and spent medium.