The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Aug. 01, 2005
Noriyuki Kizaki, Takasago, JP;
Miho Yano, Takasago, JP;
Masahiro Funaki, Takasago, JP;
Teruaki Takesue, Takasago, JP;
Yoshihiko Yasohara, Takasago, JP;
Souichi Morikawa, Takasago, JP;
Takahisa Nakai, Takasago, JP;
Michihiko Kataoka, Kyoto, JP;
Sakayu Shimizu, Kyoto, JP;
Noriyuki Kizaki, Takasago, JP;
Miho Yano, Takasago, JP;
Masahiro Funaki, Takasago, JP;
Teruaki Takesue, Takasago, JP;
Yoshihiko Yasohara, Takasago, JP;
Souichi Morikawa, Takasago, JP;
Takahisa Nakai, Takasago, JP;
Michihiko Kataoka, Kyoto, JP;
Sakayu Shimizu, Kyoto, JP;
Kaneka Corporation, Osaka, JP;
Abstract
The present invention relates to a polypeptide having an activity to asymmetrically reduce (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol isolated from a microorganism belonging to the genus, a DNA encoding the polypeptide and a transformant that produces the polypeptide. The present invention moreover relates to a method of producing (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol utilizing the polypeptide or the transformant. Using the polypeptide or transformant of the present invention, optically active alcohols such as (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol and the like can be produced efficiently.