The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Jul. 31, 2007
Masahisa Handa, Berkeley, CA (US);
Arnold H. Horwitz, San Leandro, CA (US);
Robyn Cotter, Oakland, CA (US);
Eddie Batista, San Francisco, CA (US);
Masahisa Handa, Berkeley, CA (US);
Arnold H. Horwitz, San Leandro, CA (US);
Robyn Cotter, Oakland, CA (US);
Eddie Batista, San Francisco, CA (US);
XOMA Technology Ltd., Berkeley, CA (US);
Abstract
Recombinant expression vectors are provided comprising a 3'UTR of a light chain and an Epstein-Barr virus origin of replication. Also provided are host cells comprising such vectors and methods of producing recombinant protein with such vectors. Additional methods of producing a recombinant protein involve contacting cells with a first and second vector, each of which encode a different polypeptide chain, and wherein the second vector is present in an amount which is about 1.5 to 2.5 times as much as that of the first vector. Cells also can be transfected with a recombinant transient expression vector encoding a protein and are cultured in a medium in a membrane-enhanced culturing vessel to produce recombinant protein.