The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Jul. 21, 2006
Mark A. Emalfarb, Jupiter, FL (US);
Peter J. Punt, Houten, NL;
Cornelia Van Zeijl, Vleuten-de-Meern, NL;
Cornelius Van Den Hondel, Gouda, NL;
Mark A. Emalfarb, Jupiter, FL (US);
Peter J. Punt, Houten, NL;
Cornelia van Zeijl, Vleuten-de-Meern, NL;
Cornelius van den Hondel, Gouda, NL;
Dyadic International (USA), Inc., Jupiter, FL (US);
Abstract
The invention provides a method for the expression of exogenous DNA libraries in filamentous fungi. The fungi are capable of processing intron-containing eukaryotic genes, and also can carry out post-translational processing steps such as glyclosylation and protein folding. The invention provides for the use of fungi with altered morphology, which permits high-throughput screening and directed molecular evolution of expressed proteins. The same transformed fungi may be used to produce larger quantities of protein for isolation, characterization, and application testing, and may be suitable for commercial production of the protein as well.