The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Nov. 06, 2004
Huw Alun Davies, Epson Downs, GB;
James Mcguire, Virum, DK;
Anja Hviid Simonsen, Frederiksberg, DK;
Kaj Blennow, Molndal, SE;
Vladimir Podust, Fremont, CA (US);
Huw Alun Davies, Epson Downs, GB;
James McGuire, Virum, DK;
Anja Hviid Simonsen, Frederiksberg, DK;
Kaj Blennow, Molndal, SE;
Vladimir Podust, Fremont, CA (US);
Vermilllion, Inc., Fremont, CA (US);
Abstract
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Alzheimer's disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as Alzheimer's or non-Alzheimer's dementia or normal. The biomarkers can be detected by SELDI mass spectrometry. In addition, the invention provides appropriate treatment interventions and methods for measuring response to treatment. Certain biomarkers of the invention may also be suitable for employment as radio-labeled ligands in non-invasive imaging techniques such as Positron Emission Tomography (PET).