The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Aug. 16, 2007
Javier Alarcon, Durham, NC (US);
Kristin Weidemaier, Raleigh, NC (US);
Terry J. Amiss, Cary, NC (US);
John D. Denuzzio, Chapel Hill, NC (US);
Christopher C. Herdman, Durham, NC (US);
Ross Wayne Jacobson, Hillsborough, NC (US);
J. Bruce Pitner, Durham, NC (US);
Douglas B. Sherman, Durham, NC (US);
Javier Alarcon, Durham, NC (US);
Kristin Weidemaier, Raleigh, NC (US);
Terry J. Amiss, Cary, NC (US);
John D. Denuzzio, Chapel Hill, NC (US);
Christopher C. Herdman, Durham, NC (US);
Ross Wayne Jacobson, Hillsborough, NC (US);
J. Bruce Pitner, Durham, NC (US);
Douglas B. Sherman, Durham, NC (US);
Becton, Dickinson and Company, Franklin Lakes, NJ (US);
Abstract
A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. An optical conduit, preferably an optical fiber has an optical system at the proximal end of the optical conduit. A sensing element is attached to the distal end of the optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the sensing element includes reference groups with luminescence properties that are substantially unchanged by variations in the analyte concentrations.