The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Nov. 19, 2004
Applicants:
Beat A. Imhof, Conches, CH;
Michel Aurrand-lions, Geneva, CH;
Inventors:
Beat A. Imhof, Conches, CH;
Michel Aurrand-Lions, Geneva, CH;
Assignee:
Merck Serono S.A., Coinsins, Vaud, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); C12P 21/08 (2006.01); C12N 5/20 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to angiogenesis inhibiting molecules that are the monoclonal antibody H33 or fragments or derivatives thereof, to their use in the treatment of cancer, in particular the treatment of solid tumors and to therapeutic and diagnostic compositions comprising them. The invention relates in particular to humanized derivatives of H33 of human monoclonal antibodies having the specificity of H33.