The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Aug. 08, 2006
Kenneth a Jacobson, Silver Spring, MD (US);
Victor E Marquez, Montgomery Village, MD (US);
Kenneth A Jacobson, Silver Spring, MD (US);
Victor E Marquez, Montgomery Village, MD (US);
Abstract
The present invention provides novel nucleoside and nucleotide derivatives that are useful agonist or antagonists of P1 and P2 receptors. For example, the present invention provides a compound of formula A-M, wherein A is modified adenine or uracil and M is a constrained cycloalkyl group. The adenine or uracil is bonded to the constrained cycloalkyl group. The compounds of the present invention are useful in the treatment or prevention of various diseases including airway diseases (through A, A, P2Yreceptors), cancer (through A, P2 receptors), cardiac arrhythmias (through A1 receptors), cardiac ischemia (through A, Areceptors), epilepsy (through A, P2X receptors), and Huntington's Disease (through Areceptors).