The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Aug. 16, 2002
Stuart A. Lipton, Rancho Santa Fe, CA (US);
Dongxian Zhang, San Diego, CA (US);
Jon E. Chatterton, San Diego, CA (US);
Kevin a Sevarino, Cheshire, CT (US);
Marc Awobuluyi, San Francisco, CA (US);
Stuart A. Lipton, Rancho Santa Fe, CA (US);
Dongxian Zhang, San Diego, CA (US);
Jon E. Chatterton, San Diego, CA (US);
Kevin A Sevarino, Cheshire, CT (US);
Marc Awobuluyi, San Francisco, CA (US);
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Yale University, New Haven, CT (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Abstract
The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods.