The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Jan. 31, 2008
Applicants:
Jennifer A. Johnston, Mill Valley, CA (US);
Alfred Goldberg, Chestnut Hill, MA (US);
Inventors:
Jennifer A. Johnston, Mill Valley, CA (US);
Alfred Goldberg, Chestnut Hill, MA (US);
Assignee:
Elan Pharma International Limited, Monksland, Athlone, County Westmeath, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides in vitro and cell-based assays for parkin activity, in which parkin-mediated ubiquitination of the S5a subunit of the 26S proteasome is measured, or ubiquitination of troponin 1. The assays may be used to screen for agents that modulate parkin protein ligase activity.