The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2010

Filed:

May. 13, 2004
Applicants:

Masami Mizu, Sakai, JP;

Seiji Shinkai, Fukuoka, JP;

Kazuo Sakurai, Himeji, JP;

Kazuya Koumoto, Kitakyushu, JP;

Munenori Numata, Fukuoka, JP;

Takahiro Matsumoto, Fukuoka, JP;

Inventors:

Masami Mizu, Sakai, JP;

Seiji Shinkai, Fukuoka, JP;

Kazuo Sakurai, Himeji, JP;

Kazuya Koumoto, Kitakyushu, JP;

Munenori Numata, Fukuoka, JP;

Takahiro Matsumoto, Fukuoka, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 38/16 (2006.01); A61K 31/70 (2006.01); A61K 31/715 (2006.01); A01N 43/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a new type of immunostimulating agent including an immunostimulating oligonucleotide complexed with a carrier which is safe and has a high transfection effect. The carrier complexed with the immunostimulating oligonucleotide to form the immunostimulating agent is a polysaccharide having β-1,3-bonds (preferably β-1,3-glucan such as schizophyllan). A preferred example of the immunostimulating oligonucleotide is one containing an unmethylated CpG motif. The polysaccharide for use is preferably modified with nucleic acid-binding functional group and/or cell membrane-affinitive functional group.


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