The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2010
Filed:
Nov. 01, 2005
Milan S. Blake, Fulton, MD (US);
John A. Bogdan, Jr., Westminster, MD (US);
Javier Nazario-larrieu, Rio Piedras, PR (US);
Milan S. Blake, Fulton, MD (US);
John A. Bogdan, Jr., Westminster, MD (US);
Javier Nazario-Larrieu, Rio Piedras, PR (US);
Baxter International Inc., Deerfield, IL (US);
Bacter Healthcare S.A., Zurich, CH;
Abstract
Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.