The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
May. 08, 2006
Applicants:
Vilas A. Dahanukar, Edison, NJ (US);
Hoa N. Nguyen, Dayton, NJ (US);
Cecilia A. Orr, Clark, NJ (US);
Fucheng Zhang, Edison, NJ (US);
Ilia Zavialov, Princeton, NJ (US);
Inventors:
Vilas A. Dahanukar, Edison, NJ (US);
Hoa N. Nguyen, Dayton, NJ (US);
Cecilia A. Orr, Clark, NJ (US);
Fucheng Zhang, Edison, NJ (US);
Ilia Zavialov, Princeton, NJ (US);
Assignee:
Schering Corporation, Kenilworth, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/06 (2006.01); C07D 473/08 (2006.01); C07D 233/90 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for preparing xanthine phosphodiesterase V inhibitors, and compounds utilized in said process. The process includes a five-step methodology for efficient synthesis of Compound 5 without intermediate purifications or separations, a dihalogenation step to synthesize Compound 7, and a coupling reaction to produce Compound 9.