The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
Jan. 12, 2007
Jacqueline K. Barton, San Marino, CA (US);
Brian Zeglis, Pasadena, CA (US);
Irvin H. Lau, Pasadena, CA (US);
Jonathan Hart, San Diego, CA (US);
MI Hee Lim, San Diego, CA (US);
Jacqueline K. Barton, San Marino, CA (US);
Brian Zeglis, Pasadena, CA (US);
Irvin H. Lau, Pasadena, CA (US);
Jonathan Hart, San Diego, CA (US);
Mi Hee Lim, San Diego, CA (US);
California Institute of Technology, Pasadena, CA (US);
Abstract
In accordance with the present invention there are provided sterically demanding intercalators. These compounds are useful for detection of a base-pair mismatch, such as by measuring fluorescence of complexes formed by the compounds of the invention and nucleic acid duplexes. The compounds are also capable of catalyzing photolytic cleavage of nucleic acids.