The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
Apr. 11, 2003
Applicants:
Osvaldo A. Flores, North Wales, PA (US);
Jay Grobler, Gwynedd, PA (US);
Edward M. Murray, Limerick, PA (US);
Paul D. Zuck, Trenton, NJ (US);
Inventors:
Osvaldo A. Flores, North Wales, PA (US);
Jay Grobler, Gwynedd, PA (US);
Edward M. Murray, Limerick, PA (US);
Paul D. Zuck, Trenton, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12P 21/00 (2006.01); C12N 15/00 (2006.01); C12N 15/51 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention features assays employing a beta-lactamase reporter system, an HCV replicon enhanced cell, and/or a chimeric HCV replicon containing a 3' UTR based on the HCV-1a 3′ UTR. These features can be employed alone or together, and are preferably combined together to measure HCV replicon activity and the affect of compounds on such activity.