The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
Dec. 04, 2003
Applicant:
Vivek M. Rangnekar, Lexington, KY (US);
Inventor:
Vivek M. Rangnekar, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C12P 21/00 (2006.01); C12N 15/00 (2006.01); C12N 5/07 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to Par-4 mutants which cause apoptosis in cancer cells which are sensitive to Par-4 and also induce apoptosis in cancer cells which are resistant to Par-4. The present invention also relates to methods of using the Par-4 mutant to treat certain cancers, as well as to kits, vectors, and polypeptides for same.