The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
May. 20, 2003
Alexander James Bridges, Saline, MI (US);
William Alexander Denny, Auckland, NZ;
Ellen Myra Dobrusin, Ann Arbor, MI (US);
Annette Marian Doherty, Paris, FR;
David William Fry, Ypsilanti, MI (US);
Dennis Joseph Mcnamara, Ann Arbor, MI (US);
Howard Daniel Hollis Showalter, Ann Arbor, MI (US);
Jeffrey B. Smaill, Auckland, NZ;
Hairong Zhou, Ann Arbor, MI (US);
Alexander James Bridges, Saline, MI (US);
William Alexander Denny, Auckland, NZ;
Ellen Myra Dobrusin, Ann Arbor, MI (US);
Annette Marian Doherty, Paris, FR;
David William Fry, Ypsilanti, MI (US);
Dennis Joseph McNamara, Ann Arbor, MI (US);
Howard Daniel Hollis Showalter, Ann Arbor, MI (US);
Jeffrey B. Smaill, Auckland, NZ;
Hairong Zhou, Ann Arbor, MI (US);
Warner-Lambert Company, Morris Plains, NJ (US);
Abstract
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E, E, E, Rand p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.