The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2010

Filed:

May. 11, 2005
Applicants:

Balázs Volk, Budapest, HU;

József Barkóczy, Budapest, HU;

Gyula Simig, Budapest, HU;

Tibor Mezei, Budapest, HU;

Rita Kapillerné Dezsöfi, Budapest, HU;

Endréné Flórian, Budapest, HU;

István Gacsályi, Budapest, HU;

Katalin Pallagi, Budapest, HU;

Gábor Gigler, Budapest, HU;

György Lévay, Budakeszi, HU;

Krisztina Móricz, Budapest, HU;

Csilla Leveleki, Budapest, HU;

Nóra Sziray, Budapest, HU;

Gábor Szénási, Uröm, HU;

András Egyed, Budapest, HU;

László Gábor Hársing, Budapest, HU;

Inventors:

Balázs Volk, Budapest, HU;

József Barkóczy, Budapest, HU;

Gyula Simig, Budapest, HU;

Tibor Mezei, Budapest, HU;

Rita Kapillerné Dezsöfi, Budapest, HU;

Endréné Flórian, Budapest, HU;

István Gacsályi, Budapest, HU;

Katalin Pallagi, Budapest, HU;

Gábor Gigler, Budapest, HU;

György Lévay, Budakeszi, HU;

Krisztina Móricz, Budapest, HU;

Csilla Leveleki, Budapest, HU;

Nóra Sziray, Budapest, HU;

Gábor Szénási, Uröm, HU;

András Egyed, Budapest, HU;

László Gábor Hársing, Budapest, HU;

Assignee:

Egis Gyogyszergyar Nyrt, Budapest, HU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); C07D 209/34 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with new 3,3-disubstituted indol-2-one derivatives of the general Formula (I), wherein Rstands for hydrogen, halogen, alkyl having 1-7 carbon atom(s) or sulfonamido; Rrepresents hydrogen or halogen; Rdenotes hydrogen, alkyl having 1-7 carbon atom(s) optionally carrying an aryl substituent or aryl optionally carrying one or two halogen substituent(s); Rstands for alkyl having 1-7 carbon atom(s); Rrepresents a group of the general Formula (II a) or (II b), wherein Q and W each represents nitrogen or CH; R, Rand Reach stands for hydrogen, halogen, trifluoromethyl, alkyl or alkoxy having 1-7 carbon atom(s), or Rand Rtogether represent ethylenedioxy; m is 0, 1, or 2; a is a single, double or triple bond; n is 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof which are useful in the treatment or prophylaxis of diseases of the central nervous system, the gastrointestinal system and the cardiovascular system.


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